Fast Delivery Raw Powder Dapoxetine Hydrochloride USP Grade CAS 129938-20-1

Fast Delivery Raw Powder Dapoxetine Hydrochloride USP Grade CAS 129938-20-1

Fast Delivery Raw Powder Dapoxetine Hydrochloride USP Grade CAS 129938-20-1

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Fast delivery raw powder Dapoxetine hydrochloride usp grade cas 129938-20-1
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Product Name Dapoxetine Hydrochloride
CAS NO. 129938-20-1
MOQ 1 kg
Other Name Dapoxetine HCl
Molecular Formular C21h24cino
Molecular Weight 341.874
Appearance White powder
Brand Monad
Purity 99%
Melting Point 175-179ºC
Vapor Pressure 1.27E-09mmHg at 25°C
Boiling Point 454.4ºC at 760 mmHg
Flash Point 132.6ºC
   
Dapoxetine hydrochloride Structure
 
Dapoxetine hydrochloride Chemical Properties
Melting point  175-1790C
alpha  D +135.78° (c = 2.18 in methanol)
storage temp.  room temp
solubility  DMSO: ≥20mg/mL
form  powder
color  white
optical activity [α]/D +125 to +135°, c = 1 in methanol
Merck  14,2821
CAS DataBase Reference 129938-20-1(CAS DataBase Reference)

Description
PE is the most common form of male sexual dysfunction affecting 20-40% of men globally at some point in their lives. Ejaculation is a reflex comprising different sensory pathways, motor centers, and nerve pathways. This ejaculatory reflex has been shown to be controlled primarily by serotonin and dopamine. Dapoxetine is a short-acting SSRI. It is differentiated from the existing SSRI treatments for PE by the fact that it can be administered on an as-needed basis. In healthy subjects, dapoxetine is rapidly absorbed after oral administration with a peak plasma concentration (Tmax) occurring between 1.4 and 2 h.

Dapoxetine also showed statistically significant improvements in perceived control over ejaculation, PE-related personal distress, and other patient-reported outcomes in all five trials. Dapoxetine treatment was generally well tolerated, with low incidences of discontinuation syndrome, sexual dysfunction, and treatment-emergent mood symptoms. The most common adverse events with dapoxetine included nausea, diarrhea, headache, dizziness, and somnolence.






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