Fast Delivery Raw Powder Dapoxetine Hydrochloride USP Grade CAS 129938-20-1
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Fast delivery raw powder Dapoxetine hydrochloride usp grade cas 129938-20-1
Basic information
Description
PE is the most common form of male sexual dysfunction affecting 20-40% of men globally at some point in their lives. Ejaculation is a reflex comprising different sensory pathways, motor centers, and nerve pathways. This ejaculatory reflex has been shown to be controlled primarily by serotonin and dopamine. Dapoxetine is a short-acting SSRI. It is differentiated from the existing SSRI treatments for PE by the fact that it can be administered on an as-needed basis. In healthy subjects, dapoxetine is rapidly absorbed after oral administration with a peak plasma concentration (Tmax) occurring between 1.4 and 2 h.
Dapoxetine also showed statistically significant improvements in perceived control over ejaculation, PE-related personal distress, and other patient-reported outcomes in all five trials. Dapoxetine treatment was generally well tolerated, with low incidences of discontinuation syndrome, sexual dysfunction, and treatment-emergent mood symptoms. The most common adverse events with dapoxetine included nausea, diarrhea, headache, dizziness, and somnolence.
Basic information
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| Product Name | Dapoxetine Hydrochloride |
| CAS NO. | 129938-20-1 |
| MOQ | 1 kg |
| Other Name | Dapoxetine HCl |
| Molecular Formular | C21h24cino |
| Molecular Weight | 341.874 |
| Appearance | White powder |
| Brand | Monad |
| Purity | 99% |
| Melting Point | 175-179ºC |
| Vapor Pressure | 1.27E-09mmHg at 25°C |
| Boiling Point | 454.4ºC at 760 mmHg |
| Flash Point | 132.6ºC |
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| Dapoxetine hydrochloride Chemical Properties |
| Melting point | 175-1790C |
| alpha | D +135.78° (c = 2.18 in methanol) |
| storage temp. | room temp |
| solubility | DMSO: ≥20mg/mL |
| form | powder |
| color | white |
| optical activity | [α]/D +125 to +135°, c = 1 in methanol |
| Merck | 14,2821 |
| CAS DataBase Reference | 129938-20-1(CAS DataBase Reference) |
Description
PE is the most common form of male sexual dysfunction affecting 20-40% of men globally at some point in their lives. Ejaculation is a reflex comprising different sensory pathways, motor centers, and nerve pathways. This ejaculatory reflex has been shown to be controlled primarily by serotonin and dopamine. Dapoxetine is a short-acting SSRI. It is differentiated from the existing SSRI treatments for PE by the fact that it can be administered on an as-needed basis. In healthy subjects, dapoxetine is rapidly absorbed after oral administration with a peak plasma concentration (Tmax) occurring between 1.4 and 2 h.
Dapoxetine also showed statistically significant improvements in perceived control over ejaculation, PE-related personal distress, and other patient-reported outcomes in all five trials. Dapoxetine treatment was generally well tolerated, with low incidences of discontinuation syndrome, sexual dysfunction, and treatment-emergent mood symptoms. The most common adverse events with dapoxetine included nausea, diarrhea, headache, dizziness, and somnolence.
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